Industrial Technology Research Institute of Hsinchu, Taiwan, received US Patent No. 6,528,291, “Activated inorganic slide having aldehyde groups deposited by plasma.” The patent covers a method for using plasma deposition to create an active slide, which is usable for microarrays, with a layer of actively functional groups of polymers.
Boston Probes of Medford, Mass., received US Patent No. 6,528,267, “Methods, kits and compositions pertaining to PNA molecular beacons.” The patent covers a system for creating PNA molecular beacons, which are self-complementary arm segments, and flexible linkages for molecular interactions. In the absence of a target sequence, PNA molecular beacons facilitate energy transfer between the linked donor and acceptor moieties of the probe, and can be used in microarray analysis.
Nanogen of San Diego received US Patent No. 6,524,517, “Methods for molding and grafting highly uniform polymer layers onto electronic microchips.” The patent covers a system for creating microreaction molds, from materials such as etched silica, or multicomposite, such as quartz/metal, and methods for molding uniform thin films onto substrates. The molds can be used to generate thin polymeric films onto microchip substrates, and can be used to create microarrays.