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Indiana University School of Medicine, Microarray Technology, University of Chicago, Takeda Chemical Industries


Indianapolis Life Sciences Incubator Gets $2.3M Federal Funding

Indiana University School of Medicine’s Emerging Technology Center will get $2.25 million in the FY 2003 federal funding bill approved by Congress last week.

The center, located in Indianapolis and scheduled to open in April, will serve as an incubator for life sciences research startups and is part of the Central Indiana Life Sciences Initiative, a collaborative effort between private industry, government, and Indiana and Purdue Universities to nurture life sciences business. Part of the effort includes the Indiana Genomics Initiative, which was funded with a $105 million gift from Lilly Endowment to Indiana University in 2000.

Construction on the 60,000 square-foot three-year-old building purchased for $4 million started in January. When completed it will include dry and wet lab space and will rent for an estimated $9.50 a square foot. It is similar to incubators in Cincinnati, Cleveland, and St. Louis. Businesses incubated there will be required to establish themselves in the state and remain there for as long as they were in the facility.


Estimating Growth in the Microarray Market

Another crystal-ball reader took a shot at divining the future of the microarray technology industry last week, and found . . . a rosy financial future. The industry could surpass $5 billion by 2010, according to a study released by Kalorama Information, a division of New York-based

The $3,500 survey, “U.S. Markets in Analytical Chip Technology: Gene, Protein, Tissue, Cell, and Microbiological Microarrays” sees chip assay technologies taking root broadly across life sciences research in coming decades, but says drug discovery is the immediate opportunity.

The study examines DNA/gene, protein, cell, tissue, and microbiology microarrays.

So, add this study to the financial prognostications that see the microarray market measuring some $500 million a year today, and growing, year over year, based on projections from revenues provided by public companies like Affymetrix, Agilent, and others engaged in producing microarrays. To date, no analysis has actually created a data picture that reflects the nuances of this emerging market, satisfactorily combining product revenues, sales of chemicals, services, instrumentation, as well as venture capital investment, and government funding — in a global context — to paint a granular and thorough picture of this market.


Microarray Workshop in Chicago

The University of Chicago is offering an Affymetrix GeneChip microarray workshop May 12-16. There is space for 20 participants and the fee is $2,000 per attendee. For further information, please contact Dr. Xinmin Li at [email protected] or the website at

The workshop provides hands-on experience and includes target preparation, chip hybridization, and advanced data analysis. The workshop starts with RNA quality evaluation, using an Agilent 2100 bioanalyzer and finishes with independent confirmation using real-time PCR. The course will cover experimental design, noise filtration, data visualization, and interpretation. Computational laboratory sessions will introduce several bioinformatics and computational approaches to microarray analysis.

The workshop is sponsored by the functional genomics facility in conjunction with the bioinformatics and computational biology core facility, NIDDK biotechnology center, and the biological sciences collegiate division.


Takeda Chemical Expands Access to Gene Logic GeneExpress Products

Takeda Chemical Industries, a Japanese pharmaceuticals company, has expanded its GeneExpress license, Gene Logic said this week. The company now has complete access to BioExpress data and the ToxExpress Predictive System. Financial details were not disclosed.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.