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Imaging Research and Contentsoft

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Imaging Research of St. Catharines, Canada, has released version 7.0 of its ArrayVision image analysis software. The new version includes a protein analysis module to analyze protein arrays in microplates and on slides. Further information and a downloadable evaluation version of ArrayVision are available at www.imagingresearch.com.

Contentsoft of Munich, Germany has released GeneViz 2.0, a microarray data analysis tool featuring double conjugated clustering, singular value decomposition sorting, and principal component analysis with 3D visualization. The software is freely available to qualifying non-commercial institutions at www.contentsoft.de/download.php.

The Scan

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.

Breast Cancer Risk Gene Candidates Found by Multi-Ancestry Low-Frequency Variant Analysis

Researchers narrowed in on new and known risk gene candidates with variant profiles for almost 83,500 individuals with breast cancer and 59,199 unaffected controls in Genome Medicine.

Health-Related Quality of Life Gets Boost After Microbiome-Based Treatment for Recurrent C. Diff

A secondary analysis of Phase 3 clinical trial data in JAMA Network Open suggests an investigational oral microbiome-based drug may lead to enhanced quality of life measures.

Study Follows Consequences of Early Confirmatory Trials for Accelerated Approval Indications

Time to traditional approval or withdrawal was shorter when confirmatory trials started prior to accelerated approval, though overall regulatory outcomes remained similar, a JAMA study finds.