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Illumina, SuperArray, Axaron Bioscience, Epicentre, Case Western Reserve University, Fisheries Research Agency


Illumina has begun shipping its new Oligator mouse genome oligo set for spotted gene expression arrays. The Mouse Exonic-Evidence-Based Oligonucleotide set contains 38,467 70-mer probe sequences and is designed for studying mouse transcription and alternative splicing patterns.

SuperArray has launched its RT2 Real-Time and RT2 End-Point PCR gene expression assay kits. The kits offer primer sets for every gene in the human, mouse, and rat genomes, as well as several PCR master mixes accommodating different PCR instruments.

Axaron Bioscience has developed the Axaminer platform for cell-type specific transcription profiling. The platform is being used in developing the firm’s Phase II stroke treatment, AX200, as well as in a study investigating the mode of action of antidepressant amitriptyline.

Epicentre has announced the availability of its ArrayPure Nano-scale RNA Purification Kit. According to the firm, the kit provides all reagents necessary to purify RNA from one to 10,000 eukaryotic cells.

Case Western Reserve University announced that its BAMarray software is now available for download and licensing. The BAMarray software analyzes gene expression data and was developed by researchers at Case Western and the Cleveland Clinic Foundation Departments of Biostatistics and Epidemiology.

Japan’s Fisheries Research Agency has developed a DNA chip-based diagnostic product for detecting 23 different pathogenic bacteria in fish.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.