Illumina of San Diego, Calif., has received US Patent No. 6,942,968, "Array compositions for improved signal detection." The patented invention is used for methods of improving signal detection from an array and methods for background subtraction in an array. The invention provides for array compositions including arrays with wells with different shapes, or surfaces coated with reflective or selectively absorptive coatings. In addition, the patented array includes a signal transducer element.