Skip to main content
Premium Trial:

Request an Annual Quote

IconoClust, Microarray Database of Gene Expression (MADGE)


Clondiag chip technologies of Jena, Germany, has released IconoClust, an array imaging software that allows automated analysis of both individual array images and groups of array images. The software allows users to import files from an arraying system, such as *.gal files, and to use them. The software includes an image browser that enables rapid import and processing of images. The data processing script for analysis of images can be modified or generated by the user, the company said. The software includes interfaces that can integrate it with other databases including laboratory information management systems. The software is available for download and a free one-month test from the company’s website, ?jump=products. For a fee of $400 or €420, the software can also be licensed for an unlimited time.

Richard McIndoe, a professor of pathology at the University of Florida College of Medicine, and his staff at the department’s microarray facility, have developed a Microarray Database of Gene Expression, (MADGE). The database uses a three-tier client server model. The first tier includes a relational database system, SQL Server v. 7.0. The second layer is an object-oriented data services layer, in the form of a distributed COM server, that enables access to the underlying database tables. The third layer is an internet-based user interface. The system will be available for the academic community to license within a month. Information about MADGE will be available at resources/software.htm.


The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.