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Hyseq & MicroDiscovery GmbH


Hyseq of Sunnyvale, Calif., has received US Patent Number 6,355,419, “Preparation of pools of nucleic acids based on representation in a sample.” The invention covers methods for preparing pools for use in hybridizations. Nucleic acids that are represented to a similar degree within a sample are pooled. The method allows the user to control hybridization conditions, such as temperature, ionic strength, and time, in order to increase the likelihood that the nucleic acids within each pool hybridize to a probe with an intensity that is detectable but not saturating to the probe. Additionally, the invention describes arrays and kits that include these pooled nucleic acids, as well as a method for identifying a nucleic acid within a sample.


MicroDiscovery GmbH of Berlin has received German Patent Number DE0010025384A1,”Quantitative measurement of molecule amounts in complex mixtures.” The invention described in the patent relates to a process for the quantitative measurement of molecule amounts in complex mixtures using microarrays and other analogous carriers. Fields of application for this invention are molecular biology, medicine, and the pharmaceutical industry.

The Scan

Response Too Slow, Cautious

A new report criticizes the global response to the threat of the COVID-19 pandemic, Nature News reports.

Pushed a Bit Later

Novavax has pushed back its timeline for filing for authorization for its SARS-CoV-2 vaccine, according to Bloomberg.

AMA Announces Anti-Racism Effort

The Associated Press reports that the American Medical Association has released a plan to address systemic racism in healthcare.

Nucleic Acids Research Papers on miRMaster 2.0, MutationTaster2021, LipidSuite

In Nucleic Acids Research this week: tool to examine small non-coding RNAs, approach to predict ramifications of DNA variants, and more.