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HybChamber Mica, Outlook for DNA Microarrays: Emerging Applications and Insights on Optimizing Microarray Studies


GeneMachines has introduced its HybChamber Mica model, which it said is designed to protect light-sensitive fluorophores during hybridization of microarrays. The new chamber includes a semitransparent cover that reduces visible light transmittance 25 percent compared to the company’s standard HybChamber, a GeneMachines press statement said. The chamber, which has room for two slides, also allows for sample monitoring during hybridization.

“With users demanding more from their microarray expression data, the new HybChamber Mica models offer an added layer of protection in maintaining experimental control and reproducibility,” said Keith Gulyas, GeneMachines molecular applications group Leader, in a statement.

Cambridge Healthtech Institute has released a new report, Outlook for DNA Microarrays: Emerging Applications and Insights on Optimizing Microarray Studies. The report, written by Jack Pollard of Cambridge, Mass.,-based consulting firm 3rd Millennium, with Beth Castrodale and Malorye Branca from CHI, examines the way that researchers are using microarrays in drug target identification and validation, diagnostics, and lead optimization; as well as the changing business outlook for the microarray sector. It includes a chapter on optimizing microarrays, compares DNA and protein arrays, addresses the issue of alternative splicing, looks at the downstream movement of microarrays from research to the clinic; and discusses novel methods of microarray analysis.


The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.