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Howard Birndorf, David Ludvigson, William Respess, Robert Saltmarsh, Graham Lidgard, Lloyd Miller, Nicholas Kefalides, Heino von Prondzynski, David Barker

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Nanogen last week reported it has signed a new contract with chairman and CEO Howard Birndorf for a three-year, $520,000 deal that offers potential bonuses that may be as much as 80 percent of his base salary. 
 
The company also has signed new contracts with officers David Ludvigson, William Respess, Robert Saltmarsh, and Graham Lidgard: Ludvigson will receive a base salary of $360,000 with a $180,000 bonus potential; Lidgard will receive $290,000 with a $116,000 bonus potential; Respass will receive $329,000 with a $130,000 bonus potential; and Saltmarsh will receive $257,000 with a $103,000 bonus potential.
 

 
Gene Logic has named investment adviser Lloyd Miller to the company’s board of directors, the company said last week. Miller now “may be deemed to beneficially own” 4.5 million shares in the company, or 14.3 percent of its outstanding shares.
 
With the election to the board, Miller was given a grant of options to buy 30,000 shares of common stock at $1.91 a share, which would be exercisable in four installments beginning in February 2008.
 

 
SensiGen this week said Nicholas Kefalides has joined its scientific advisory board. 

Kefalides holds a Bachelor’s degree from Augustana College in Rock Island, Ill., and an MD degree from the University of Illinois College of Medicine

He said SensiGen’s AttoSense technology is a “major breakthrough” in detecting viruses and gene products that signal early onset of disease, and that he is “particularly interested in the application of this new technology on the early detection of kidney disease.”

 

 
Epigenomics has proposed electing former Roche Diagnostics CEO Heino von Prondzynski to its supervisory board. The vote would take place during Epigenomics’ next annual general meeting of shareholders. The company made the decision during a March 1 meeting of its supervisory board.
 
If elected, von Prondzynski would replace Zymogenetics CEO Bruce L.A. Carter  .
Von Prondzynski, who said he has known Epigenomics since 2002 when the company and Roche became partners, has “been convinced that their DNA methylation approach to molecular diagnostics is unique and bound to become an integral part of early cancer diagnosis and prognosis."
 

 
NextBio this week said it has appointed to its board former Illumina CSO David Barker.
 
NextBio has created a search engine and content knowledgebase that “seamlessly integrates heterogeneous data from all life science sources, changing the way researchers and clinicians work," Barker said in a statement.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.