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Gregory McGuinness, Christophe Jean, Bernd Brust, Susan Lambert

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Gregory McGuinness has joined NimbleGen Systems as vice president of international business. 
 
Prior to joining NimbleGen, McGuinness was director of European business development for Gene Logic. He spent several years as director of channel management at Affymetrix and as director of sales and distributor relations at Genetic MicroSystems. Prior to GMS, McGuinness also worked for Stratagene and PerkinElmer.  
 
McGuinness holds a BS in pharmacology, toxicology, and molecular biology from University College Dublin. He also has a diploma in management studies from Oxford Brookes University and a master’s degree in international business from Trinity College Dublin.
 

 
ExonHit Therapeutics has appointed Christophe Jean to its supervisory board.
 
Jean is currently executive vice president in charge of strategic planning at Ipsen. Jean has previously served in operations for nearly two decades at Ciba Geigy, and then at Novartis Pharma and as president at Pierre Fabre Medicament
 

 
Invitrogen has promoted Bernd Brust to senior vice president of sales for Europe and the Americas, a newly created position at the company. He had been general manager and vice president of European operations.
 
Brust has been with Invitrogen since 2004 and served as sales and marketing manager at GE Medical Systems Information Technologies. The company said Brust’s direct marketing and web marketing work, along with persistent growth in his region, spurred it to create the new position. 
 
Invitrogen said Susan Lambert, vice president of European sales, will take over Brust’s previous role.

The Scan

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Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.