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Gentel Biosciences, NuGen Technologies, Epicentre Biotechnologies, Asuragen

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Gentel Biosciences this week launched its APiX Cancer Biomarker Array Kit.
 
The single-capture antibody microarray- and protein-labeling system measures the relative abundance of forty-seven human cancer-related proteins in eight serum samples simultaneously, Gentel said.
 
APiX uses PATH ultra-thin nitrocellulose film array slides. Each kit is priced at $1,300.
 

 
NuGen Technologies this week launched its WT-Ovation Exon Module, a new part of its sample-preparation offering that is designed to enable amplification of RNA for analysis using Affymetrix GeneChip Exon and Gene ST Arrays.
 
Users will now be able to transform as little as 100 picograms of total RNA into targets for hybridization, allowing them to process samples from formalin-fixed, paraffin-embedded tissue; laser-captured, micro-dissected tissue; fine-needle aspirates; sorted cells; and frozen tissue.
 
Other components of NuGen’s sample-prep workflow include the WT-Ovation Pico or FFPE RNA Amplification Systems, and the FL-Ovation cDNA Biotin Module V2 for fragmentation and labeling of the cDNA targets.
 

 
Epicentre Biotechnologies this week launched its TargetAmp Nano-g Biotin-aRNA Labeling Kit for use with Illumina microarrays.
 
The kit produces microgram amounts of biotin-aRNA for hybridization to Illumina Expression BeadChips from as little as 25 nanograms of total RNA.
 

 
Asuragen recently upgraded its microRNA profiling services. Its DiscovArray miRNA Expression Profiling Service, initially launched in August, now requires as little as 50 nanograms of total RNA input. Previously, DiscovArray required 100 nanograms of total RNA input.
 
Additionally, Asuragen’s miRInform miRNA data packaging system — which provides normalized miRNA data in a DVD format to users — has been upgraded to support Agilent miRNA array data.
 

Asuragen is also now offering Applied Biosystems TaqMan Human v 1.0 miRNA Array as well as a miRNA-compatible sample preparation service for PAXgene blood samples.

The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.