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Genpathway

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Genpathway last week launched its Methylated DNA IP-on-Chip assays using Affymetrix GeneChip Tiling Arrays.
 
The assays include the Methylated DNA IP-on-Chip/Tiling assay, a Genome-wide assay using whole-genome tiling arrays; the Methylated DNA IP-on-Chip/Promoter assay for detection of methylated DNA in promoter regions; and the Methylated DNA Query assay for gene-by-gene analysis based on quantitative PCR.
 
According to Genpathway, the methylation assays, as well as analysis and services, will target pharmaceutical, biotechnology, and academic researchers. The assays could be used in biomarker discovery, drug target identification and validation, compound screening, and patient diagnosis and screening, the company said.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.