GenomeWeb Feature: New Techniques Driving Research into Epigenetic Changes in Cancer | GenomeWeb

NEW YORK (GenomeWeb News) – In cancer cells, all sorts of functions go awry. In addition to genetic changes, many times there are also epigenetic changes.

DNA methylation typically regulates gene expression, but in cancer that, and other epigenetic controllers, don't act quite as they are supposed to. In many cancers, there is global hypomethylation of DNA, though there is also, paradoxically, hypermethylation at some CpG island promoters, especially in the promoters of tumor suppressor genes.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

In Science this week: new single-cell RNA sequencing technique to study proliferating cells, and more.

South African researchers uncover bone cancer in an ancient hominin ancestor.

English bulldogs suffer from low genetic diversity and might have to be outbred to improve their health, according to a new study.

Theresa May tries to reassure researchers about the UK's commitment to science, New Scientist reports.