GenomeWeb Feature: New Techniques Driving Research into Epigenetic Changes in Cancer | GenomeWeb

NEW YORK (GenomeWeb News) – In cancer cells, all sorts of functions go awry. In addition to genetic changes, many times there are also epigenetic changes.

DNA methylation typically regulates gene expression, but in cancer that, and other epigenetic controllers, don't act quite as they are supposed to. In many cancers, there is global hypomethylation of DNA, though there is also, paradoxically, hypermethylation at some CpG island promoters, especially in the promoters of tumor suppressor genes.

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In Nucleic Acids Research this week: personal genome approach to RNA-seq read alignment, hematopoietic Systems Biology Repository, and more.

A man is using DNA evidence to argue that he is the rightful heir to the baronetcy of Stichill, the Guardian reports.

As part of an effort to get a diverse group of people to donate their DNA for research, some blood donors in the San Diego area will get their genomes sequenced, according to KPBS.

The comment period on the Department of Health and Human Services' proposal to alter the Common Rule has been extended.

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This online seminar will discuss a metagenomic assay to identify viruses and other pathogenic microorganisms in human tumor samples, with the aim of gaining a more comprehensive understanding of the role of the microbiome in cancer development and treatment.