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Genisphere, Progenika

Genisphere last week launched its RampUP two-round linear RNA amplification kit. The kit is designed to be used with intact or degraded RNA samples, such as those extracted from formalin-fixed paraffin-embedded tissues or collected from cells through laser capture microdissection. 
According to Genisphere, the RampUP kit uses its tandem RNA polymerase promoters and can yield amplified RNA adaptable to any RNA expression platform, including qRT-PCR, glass microarrays, or Affymetrix GeneChips.

Progenika recently launched its Bloodchip, an allele-specific oligonucleotide array designed to determine blood groups by genotyping.
The current version of the array tests for the blood groups MNS, Dombrock, Kidd, Duffy, RhCE, Diego, Colton and Kell, blood groups. A test for the RhD and ABO blood groups will be added soon, the company said.
The Derio, Spain-based firm claims that the array can enable clinicians to avoid the adverse reactions that occur in patients that receive blood products.

Bloodchip is sold as a kit comprising the chip and all reagents for sample preparation with the exception of DNA preparation. The company recommends the use of Ventana Medical SystemsDiscovery Hybridization Station for the hybridization step.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.