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GeneXP Biosciences, Genomic Solutions

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GeneXP Biosciences of Woburn, Mass., this week announced the launch of the 96-well Rat Gene BioGridArray (BGA), designed for rapid gene-expression studies of toxicity. GeneXP developed the Rat Gene BGA by choosing genes regulated in response to stress or exposure to toxicants, according to publicly available data. Each well of the BGA microplate contains the same array of 173 genes printed in duplicate as well as a number of housekeeping and control genes. Complete annotation is also provided for each gene to facilitate the interpretation of data. The Rat Gene BGA is currently available as part of GeneXP Biosciences’ outsourced service for gene-expression studies, or as an installed solution in customer labs. Pricing details were not disclosed.


Genomic Solutions this week introduced HydroShear, an automated system for fragmenting DNA strands. The software driven product shears DNA in volumes as small as 40 microliters and randomly fractures it to within a two-fold size distribution consistently.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.