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Funding Update: Recent Microarray-Related NIH Grants: Aug 16, 2011

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Microarray-Related NIH Grants, May 24 – Aug. 9, 2011 (Part two of two. Part one is available here.)

Mechanisms of Cell Corpse Clearance
Principal investigator: Kimberly McCall
Organization: Boston University
Project start date: July 5, 2011
Project end date: Feb. 28, 2015
NIH institute: NIGMS
FY 2011 funding amount: $310,650


Peripheral Blood Genomic Biomarkers for Primary Fibromyalgia
Principal investigator: Sunil Kurian
Organization: Scripps Research Institute
Project start date: July 5, 2011
Project end date: June 30, 2013
NIH institute: NINR
FY 2011 funding amount: $234,330


Genetic Basis of Genotype-by-Environment Interactions Underlying Physiological Modifications
Principal investigator: Laura Reed
Organization: University of Alabama at Tuscaloosa
Project start date: July 5, 2011
Project end date: March 31, 2016
NIH institute: NIGMS
FY 2011 funding amount: $285,745


Retinoic Acid, Its Receptors, and the Liver
Principal investigator: Yu-Jui Wan
Organization: University of Kansas Medical Center
Project start date: July 6, 2011
Project end date: April 30, 2015
NIH institute: NIDDKD
FY 2011 funding amount: $375,000


Contribution of Novel Frimbriae to Proteus mirabilis Virulence
Principal investigator: Melanie Pearson
Organization: New York University School of Medicine
Project start date: July 7, 2011
Project end date: May 31, 2013
NIH institute: NIAID
FY 2011 funding amount: $161,241


The Effects of Follicular Helper T Cells on Germinal Center B Cells
Principal investigator: Heidi Schreiber
Organization: Rockefeller University
Project start date: July 11, 2011
Project end date: July 10, 2014
NIH institute: NIAID
FY 2011 funding amount: $46,346


Immune Array and Bioinformatics
Principal investigator: Rafick-Pierre Sekaly
Organization: Oregon Health and Science University
Project start date: July 15, 2011
Project end date: June 30, 2016
NIH institute: N/A
FY 2011 funding amount: $325,359


Systems Biology
Principal investigator: Rafick-Pierre Sekaly
Organization: Beth Israel Deaconess Medical Center
Project start date: July 15, 2011
Project end date: June 30, 2016
NIH institute: N/A
FY 2011 funding amount: $712,541


Diagnostic Array for Aseptic Encephalitis
Principal investigator: Darrell Chandler
Organization: Akonni Biosystems
Project start date: July 15, 2011
Project end date: June 30, 2012
NIH institute: NIAID
FY 2011 funding amount: $300,000


Development of anIn Vivo Screening Technology for Cancer Vaccine Immunogens
Principal investigator: Steven Zeichner
Organization: Children's Research Institute
Project start date: July 19, 2011
Project end date: June 30, 2014
NIH institute: NCI
FY 2011 funding amount: $227,310

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Platform for High-Throughput Analysis of Protein Adducts for Carcinogen Exposure
Principal investigator: Anthony DeCaprio
Organization: Florida International University
Project start date: July 20, 2011
Project end date: June 30, 2014
NIH institute: NCI
FY 2011 funding amount: $205,038


Novel Antiviral Activities of Tumor Necrosis Factor-Alpha
Principal investigator: Lynn Dustin
Organization: Rockefeller University
Project start date: July 27, 2011
Project end date: June 30, 2016
NIH institute: NIAID
FY 2011 funding amount: $423,750


BMP Induced Regeneration of an Endochondral Growth Zone in Digit Regeneration
Principal investigator: Ling Yu
Organization: Tulane University
Project start date: Aug. 1, 2011
Project end date: July 31, 2013
NIH institute: NICHHD
FY 2011 funding amount: $75,250


Molecular Signatures for Outcome Prediction and Therapeutic Targeting in ALL
Principal investigator: Cheryl Willman
Organization: University of New Mexico
Project start date: Aug. 1, 2011
Project end date: July 31, 2016
NIH institute: NCI
FY 2011 funding amount: $600,000


Comprehensive Prostate Cancer Characterization by Genomic and Transcriptomic Profiling
Principal investigator: Mark Rubin
Organization: Weill Medical College of Cornell University
Project start date: Aug. 1, 2011
Project end date: July 31, 2014
NIH institute: NCI
FY 2011 funding amount: $612,154


First Transcriptome to the Tick Olfactory System
Principal investigator: Richard Roe
Organization: North Carolina State University at Raleigh
Project start date: Aug. 1, 2011
Project end date: July 30, 2013
NIH institute: NIAID
FY 2011 funding amount: $236,083


Dynamic Usage of Network Motifs in Retinal Development and Diseases
Principal investigator: Jiang Qian
Organization: Johns Hopkins University
Project start date: Aug. 1, 2011
Project end date: July 31, 2013
NIH institute: NEI
FY 2011 funding amount: $202,500


Role of JMJD1A in Hypoxia-Induced EMT and Prostate Cancer
Principal investigator: Jianfei Qi
Organization: Sanford-Burnham Medical Research Institute
Project start date: Aug. 1, 2011
Project end date: July 31, 2011
NIH institute: NCI
FY 2011 funding amount: $107,654


Molecular and Architectural Mechanisms of Reprogramming to Pluripotency
Principal investigator: Kathrin Plath
Organization: University of California at Los Angeles
Project start date: Aug. 1, 2011
Project end date: July 31, 2016
NIH institute: NIGMS
FY 2011 funding amount: $2,292,305


Amino Acid Regulation of Alternative Splicing
Principal investigator: Michael Kilberg
Organization: University of Florida
Project start date: Aug. 1, 2011
Project end date: July 31, 2015
NIH institute: NIDDK
FY 2011 funding amount: $364,082


Cell Epigenotype Specific Maps in the Brain
Principal investigator: Zachary Kaminsky
Organization: Johns Hopkins University
Project start date: Aug. 1, 2011
Project end date: July 31, 2013
NIH institute: NIMH
FY 2011 funding amount: $246,000

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The Transfusion Chip: a Simple, Low Cost Microarray for DNA Based Blood Typing
Principal investigator: Michael Hogan
Organization: Genomics USA
Project start date: Aug. 1, 2011
Project end date: Jan. 31, 2012
NIH institute: NHLBI
FY 2011 funding amount: $115,762


Escape from Gammaherpesvirus-Induced mRNA Destruction
Principal investigator: Britt Glaunsinger
Organization: University of California at Berkeley
Project start date: Aug. 1, 2011
Project end date: May 31, 2016
NIH institute: NCI
FY 2011 funding amount: $305,527


Bone-Induced C-Kit in Prostate Cancer Cells: Implications for Bone Metastasis
Principal investigator: Ricardo Bonfil
Organization: Wayne State University
Project start date: Aug. 1, 2011
Project end date: July 31, 2013
NIH institute: NCI
FY 2011 funding amount: $198,360


Microglial Activation by N-arachidonoyl Glycine
Principal investigator: Heather Bradshaw
Organization: Indiana University at Bloomington
Project start date: Aug. 1, 2011
Project end date: May 31, 2013
NIH institute: NIDA
FY 2011 funding amount: $231,000


Mechanisms of Frailty in HIV-1 Infection
Principal investigator: Kristine Erlandson
Organization: University of Colorado at Denver
Project start date: Aug. 1, 2011
Project end date: July 31, 2013
NIH institute: NIA
FY 2011 funding amount: $76,500


Complement Inhibition as Sepsis Therapy
Principal investigator: Florea Lupu
Organization: Oklahoma Medical Research Foundation
Project start date: Aug. 2, 2011
Project end date: April 30, 2015
NIH institute: NIGMS
FY 2011 funding amount: $535,225


Cell Mimic Microarrays for the Multivalent Pathogen Profiling & Characterization
Principal investigator: Athena Guo
Organization: Microsurfaces
Project start date: Aug. 3, 2011
Project end date: July 31, 2013
NIH institute: NIAID
FY 2011 funding amount: $375,000


Evaluation of Sample Sizes Used to Train Classifiers and Prognostic Predictors
Principal investigator: Kevin Dobbin
Organization: University of Georgia
Project start date: Aug. 4, 2011
Project end date: July 31, 2013
NIH institute: NCI
FY 2011 funding amount: $161,494

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.