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Funding Update: Sep 7, 2010

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NIH Microarray Grants Awarded April – August 2010, Part II of II

Shared Laboratory Resource Core
Principal investigator: Jorge Arevalo
Organization: University of California, San Diego
Project start date: July 1, 2010
Project end date: June 30, 2017
NIH institute: NIAID
FY 2010 funding amount: $211,058


DNA Methylation-based Assays for Detecting Disease Spread in Rhabdomyosarcoma
Principal investigator: Frederic Barr
Organization: University of Pennsylvania
Project start date: July 1, 2010
Project end date: June 30, 2012
NIH institute: NCI
FY 2010 funding amount: $174,000


Expression and Function of microRNA in Autoimmune Sjögren's Syndrome
Principal investigator: Seunghee Cha
Organization: University of Florida
Project start date: July 1, 2010
Project end date: June 30, 2015
NIH institute: NIDCR
FY 2010 funding amount: $366,250


Drug Resistant Pathways in Relapsed Acute Lymphoblastic Leukemia
Principal investigator: William Carroll
Organization: New York University
Project start date: July 1, 2010
Project end date: April 30, 2015
NIH institute: NCI
FY 2010 funding amount: $605,310


Novel Antigen Identification for an Enterotoxigenic E. coli Vaccine
Principal investigator: James Fleckenstein
Organization: University of Tennessee
Project start date: July 1, 2010
Project end date: June 30, 2015
NIH institute: NIAID
FY 2010 funding amount: $405,798


Genome-wide Association to Staphylococcus Carriage
Principal investigator: Eric Brown
Organization: University of Texas
Project start date: July 1, 2010
Project end date: June 30, 2014
NIH institute: NIAID
FY 2010 funding amount: $634,435


Genomic Identification of Copy Number Variants to Identify Clefting Loci
Principal investigator: John Manak
Organization: University of Iowa
Project start date: July 1, 2010
Project end date: June 30, 2015
NIH institute: NIDCR
FY 2010 funding amount: $736,759


Multichannel Electrosonic Actuation Microarray for Cell-based Screening
Principal investigator: John Meacham
Organization: Opencell Technologies
Project start date: July 1, 2010
Project end date: June 30, 2011
NIH institute: NCRR
FY 2010 funding amount: $158,708


Thyroid Physiology Studies of Inherited Disorders
Principal investigator: Samuel Refetoff
Organization: University of Chicago
Project start date: July 1, 2010
Project end date: June 30, 2011
NIH institute: NIDDK
FY 2010 funding amount: $156,000


Genomics and Genotyping Core
Principal investigator: Alan Scott
Organization: Johns Hopkins University
Project start date: July 1, 2010
Project end date: June 30, 2017
NIH institute: NIAID
FY 2010 funding amount: $100,527


Role of Sox4 in B Cell Development
Principal investigator: Xiaoping Sun
Organization: University of Texas MD Anderson Cancer Center
Project start date: July 1, 2010
Project end date: June 30, 2012
NIH institute: NIAID
FY 2010 funding amount: $79,000


Comprehensive Genetic Characterization of Antibiotic Resistance
Principal investigator: Saeed Tavazoie
Organization: Princeton University
Project start date: July 1, 2010
Project end date: June 30, 2014
NIH institute: NIAID
FY 2010 funding amount: $398,006

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Antigen-microarray Validated Monocolonal Antibody Library for Analysis of Brain-expressed Proteins
Principal investigator: Seth Blackshaw
Organization: CDI Laboratories
Project start date: July 5, 2010
Project end date: June 30, 2011
NIH institute: NIMH
FY 2010 funding amount: $290,854


Pathobiology of C. Neoformans in the Central Nervous Systems
Principal investigator: John Perfect
Organization: Duke University
Project start date: July 6, 2010
Project end date: June 30, 2011
NIH institute: NIAID
FY 2010 funding amount: $144,321


Systems Analysis Vaccine Responses in Healthy and Hyporesponsive Humans
Principal investigator: Jacques Banchereau
Organization: Baylor Research Institute
Project start date: July 12, 2010
Project end date: June 30, 2011
NIH institute: NIAID
FY 2010 funding amount: $4,499,507


Crossprotective CTL Against Influenza
Principal investigator: Ellis Reinherz
Organization: Dana-Farber Cancer Institute
Project start date: July 12, 2010
Project end date: June 30, 2011
NIH institute: NIAID
FY 2010 funding amount: $1,500,000


Mechanisms in the Expression and Decay of Long-term Habituation Memory
Principal investigator: Robert Calin-Jageman
Organization: Dominican University
Project start date: July 15, 2010
Project end date: June 30, 2013
NIH institute: NIMH
FY 2010 funding amount: $362,442


The Illumina iScan System
Principal investigator: Kathleen Barnes
Organization: Johns Hopkins University
Project start date: July 19, 2010
Project end date: July 18, 2011
NIH institute: NCRR
FY 2010 funding amount: $209,300


Illumina iScan System with Processing Equipment for the Infinium and Goldengate BeadArray Technologies
Principal investigator: Timothy Yeatman
Organization: H. Lee Moffitt Cancer Center and Research Institute
Project start date: July 23, 2010
Project end date: July 22, 2011
NIH institute: NCRR
FY 2010 funding amount: $500,000


Inform Image Segmentation Image Analysis Software and Vectra Automation System
Principal investigator: Gustavo Ayala
Organization: Baylor College of Medicine
Project start date: Aug. 1, 2010
Project end date: July 31, 2011
NIH institute: NCRR
FY 2010 funding amount: $353,500


Mechanism of Cone Degeneration Resulting from CNG Channel Deficiency
Principal investigator: Xi-Qin Ding
Organization: University of Oklahoma
Project start date: Aug. 1, 2010
Project end date: July 31, 2015
NIH institute: NEI
FY 2010 funding amount: $370,000


Dissecting Ubiquitin Pathway Selectivity with UB-Isopeptide Microarrays
Principal investigator: James Strickler
Organization: Lifesensors
Project start date: Aug. 1, 2010
Project end date: July 31, 2011
NIH institute: NIGMS
FY 2010 funding amount: $278,218


The Function of a Single-component Chromatin Remodeling Protein FUN30 In Vivo
Principal investigator: Wei-Hua Wu
Organization: Medical College of Georgia
Project start date: Aug. 1, 2010
Project end date: July 31, 2010
NIH institute: NCI
FY 2010 funding amount: $146,315


The Function of NGO02115 in the Neisseria Gonorrhoeae Oxidative Stress Resistance
Principal investigator: Mark Anderson
Organization: Northwestern University
Project start date: Aug. 4, 2010
Project end date: Aug. 3, 2012
NIH Institute: NIAID
FY 2010 funding amount: $50,474


A Rapid Pan-Viral Microarray Diagnostic for Category A+-C Biodefense Pathogens
Principal investigator: Charles Chiu
Organization: University of California, San Francisco
Project start date: Aug. 9, 2010
Project end date: July 31, 2011
NIH institute: NIAID
FY 2010 funding amount: $888,279


Manufacture of Plastic Fiber Optic Microarray Plates for Gene Sequencing
Principal investigator: Young Noh
Organization: Nanoptics
Project start date: Aug. 13, 2010
Project end date: Jan. 31, 2011
NIH institute: NHGRI
FY 2010 funding amount: $149,500


Understanding How HIV-1 VPU and HIV-2 ENV Stimulate Virus Release
Principal investigator: Paula Cannon
Organization: University of Southern California
Project start date: Aug. 18, 2010
Project end date: July 31, 2011
NIH institute: NIAID
FY 2010 funding amount: $82,111


Heme Oxygenase: Structure, Function and Pathogenesis
Principal investigator: Angela Wilks
Organization: University of Maryland at Baltimore
Project start date: Aug. 30, 2010
Project end date: April 30, 2011
NIH institute: NIAID
FY 2010 funding amount: $300,000

The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.