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Funding Update: Jan 11, 2011

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Microarray-Related NIH Grants, Sept. 2010 – Dec. 2010

Development of a Test Cancer Biochip for the Cancer Biochip System
Principal investigator: Rula Abbud-Antaki
Organization: Falcon Genomics
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2011
NIH institute: NCI
FY 2010 funding amount: $269,640


Gene Expression Biomarkers for Diagnosis of Lyme Disease
Principal investigator: Ira Schwartz
Organization: New York Medical College
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2013
NIH institute: CDC
FY 2010 funding amount: $249,945


Integrating Experiment and Theory to Characterize Diagnostic Antibody Specificity
Principal investigator: Robert Woods
Organization: University of Georgia
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2014
NIH institute: NIGMS
FY 2010 funding amount: $305,025


Blood Systems Biology
Principal investigator: Scott Diamond
Organization: University of Pennsylvania
Project start date: Sept. 1, 2010
Project end date: June 30, 2015
NIH institute: NHLBI
FY 2010 funding amount: $771,947


Derivation of Mature Oocytes from Human Primordial Follicles
Principal investigator: Aaron Hsueh
Organization: Stanford University
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2012
NIH institute: $237,681


Matrix–Mediated Endothelial Differentiation of Induced Pluripotent Stem Cells
Principal investigator: Ngan Huang
Organization: Stanford University
Project start date: Sept. 1, 2010
Project end date: June 30, 2012
NIH institute: NHLBI
FY 2010 funding amount: $132,786


Characterization and Genetic Analysis of Aging in Daphnia
Principal investigator: Jeffry Dudycha
Organization: University of South Carolina at Columbia
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2011
NIH institute: NIA
FY 2010 funding amount: $270,255


Bioinformatics Core
Principal investigator: Mohamed Elasri
Organization: University of Southern Mississippi
Project start date: Sept. 1, 2010
Project end date: May 31, 2011
NIH institute: NCRR
FY 2010 funding amount: $204,324


Therapeutic Targets for Viral and Non-Viral Associated Oral Neoplasms
Principal investigator: David Azorsa
Organization: Translational Genomics Research Institute
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2012
NIH institute: NIDCR
FY 2010 funding amount: $253,500


PUI Research-Tougaloo-Mao
Principal investigator: Jinghe Mao
Organization: University of Southern Mississippi
Project start date: Sept. 1, 2010
Project end date: May 31, 2011
NIH institute: NCRR
FY 2010 funding amount: $80,818


Genome Characterization
Principal investigator: Matthew Meyerson
Organization: The Broad Institute
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2011
NIH institute: NCI
FY 2010 funding amount: $608,811

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PUI Research MUW Whitwam
Principal investigator: Ross Whitwam
Organization: University of Southern Mississippi
Project start date: Sept. 1, 2010
Project end date: May 31, 2011
NIH institute: NCRR
FY 2010 funding amount: $161,667


Glycoprotein Biomarkers for the Early Detection of Aggressive Prostate Cancer

Principal investigator: Hui Zhang
Organization: Johns Hopkins University
Project start date: Sept. 1, 2010
Project end date: June 30, 2015
NIH institute: NCI
FY 2010 funding amount: $466,295


Development and Commercialization of Ocular Diagnostic Tests Based on Vitreous [Proteome]
Principal investigator: Bert Glaser
Organization: Ocular Proteomics
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2011
NIH institute: NEI
FY 2010 funding amount: $177,367


Core Research Project: Human Metabolites of Algal Hepatoxins
Principal investigator: Kathleen Rein
Organization: Florida International University
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2011
NIH institute: NIEHS
FY 2010 funding amount: $467,065


Molecular Regulation of the Invasive Growth of Oral Cancer by YAP
Principal investigator: Eric Tang
Organization: University of California Los Angeles
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2012
NIH institute: NIDCR
FY 2010 funding amount: $97,200


Pathology Core
Principal Investigator: Russell Broaddus
Organization: MD Anderson Cancer Center
Project start date: Sept. 1, 2010
Project end date: Aug. 31, 2015
NIH institute: NCI
FY 2010 funding amount: $117,295


DNA Microarray
Principal investigator: Herbert Lyerly
Organization: Duke University
Project start date: Sept. 3, 2010
Project end date: Dec. 31, 2014
NIH institute: NCI
FY 2010 funding amount: $202,499


Oral Microbial Biomarkers in Periodontal Disease Progression
Principal investigator: Bruce Paster
Organization: Forsyth Institute
Project start date: Sept. 3, 2010
Project end date: Aug. 31, 2014
NIH institute: NIDCR
FY 2010 funding amount: $775,447


Establishing Drosophila Tools for Pathway Mapping and Target Identification
Principal investigator: Elena Gracheva
Organization: Medros
Project start date: Sept. 7, 2010
Project end date: Sept. 6, 2011
NIH institute: NIGMS
FY 2010 funding amount: $150,000


Proteomics and Genomics Core Facility
Principal investigator: Robert Holt
Organization: Meharry Medical College
Project start date: Sept. 8, 2010
Project end date: June 30, 2011
NIH institute: NCRR
FY 2010 funding amount: $337,529


Genetic and Environmental Determinants of Germ Cell Development and Follicle [Numbers]
Principal investigator: Sonya Schuh-Huerta
Organization: Stanford University
Project start date: Sept. 11, 2010
Project end date: Sept. 10, 2013
NIH institute: NICHD
FY 2010 funding amount: $52,154


Approaches for Genomic Mapping of 5-Hydromethylcytosine
Principal investigator: Saulius Kilmasauskas
Organization: Vilnius Institute of Biotechnology
Project start date: Sept. 14, 2010
Project end date: June 30, 2012
NIH institute: NHGRI
FY 2010 funding amount: $128,023

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A Novel All-Purpose Programmable and Scalable Biochip for Biomedical Applications
Principal investigator: Xing Cheng
Organization: Texas Engineering Experiment Station
Project start date: Sept. 15, 2010
Project end date: May 31, 2012
NIH institute: NCRR
FY 2010 funding amount: $174,830


Genomics
Principal investigator: John Coller
Organization: Stanford University
Project start date: Sept. 15, 2010
Project end date: May 31, 2015
NIH institute: NCI
FY 2010 funding amount: $166,272


Core C: Genomics and High-Throughput Screening Core
Principal investigator: Scott Diamond
Organization: Children's Hospital of Philadelphia
Project start date: Sept. 15, 2010
Project end date: June 30, 2015
NIH institute: NIDDK
FY 2010 funding amount: $259,542


Chemical Tools for Studying Fucosylated Glycans
Principal investigator: Peng Wu
Organization: Albert Einstein College of Medicine
Project start date: Sept. 15, 2010
Project end date: Aug. 31, 2015
NIH institute: NIGMS
FY 2010 funding amount: $315,400


Specimen Acquisition and Pathology
Principal investigator: Peggy Porter
Organization: Fred Hutchinson Cancer Research Center
Project start date: Sept. 15, 2010
Project end date: Aug. 31, 2015
NIH institute: NCI
FY 2010 funding amount: $113,638


Piezoelectric Pipetting for High Density Nucleic Acid Programmable Protein Arrays
Principal investigator: Peter Wiktor
Organization: Engineering Arts
Project start date: Sept. 15, 2010
Project end date: July 31, 2012
NIH institute: NCRR
FY 2010 funding amount: $213,279


Diagnostic Assay for Thrombocytosis
Principal investigator: Dmitri Gnatenko
Organization: Stony Brook Biotechnology
Project start date: Sept. 16, 2010
Project end date: Sept. 15, 2011
NIH institute: NCRR
FY 2010 funding amount: $178,894


CAT1920: A Small Molecule Therapeutic for the Treatment of IBD
Principal investigator: Michael Jirousek
Organization: Catabasis Pharmaceuticals
Project start date: Sept. 16, 2010
Project end date: Aug. 30, 2011
NIH institute: NIAID
FY 2010 funding amount: $179,900


Genomics Profiling
Principal investigator: Lisa White
Organization: Baylor College of Medicine
Project start date: Sept. 17, 2010
Project end date: June 30, 2015
NIH institute: NCI
FY 2010 funding amount: $165,765


Diagnostic MDR- and XDR-TB TruArray
Principal investigator: Darrell Chandler
Organization: Akonni Biosystems
Project start date: Sept. 20, 2010
Project end date: Aug. 31, 2013
NIH institute: NIAID
FY 2010 funding amount: $2,985,932


Epigenetic Programming of Brain Development by Choline Nutrition
Principal investigator: Jan Blusztajn
Organization: Boston University
Project start date: Sept. 20, 2010
Project end date: May. 31, 2012
NIH institute: NICHD
FY 2010 funding amount: $243,750

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Microarray
Principal investigator: Jacqueline Lees
Organization: Massachusetts Institute of Technology
Project start date: Sept. 20, 2010
Project end date: April 30, 2015
NIH institute: NCI
FY 2010 funding amount: $41,419


Role of the Gut Microbiota and TLR4 in Alcoholic Hepatocarcinogenesis
Principal investigator: Robert Schwabe
Organization: Columbia University
Project start date: Sept. 20, 2010
Project end date: Aug. 31, 2015
NIH institute: NIAAA
FY 2010 funding amount: $431,663


High-Throughput Low Cost Production of Chromatin-Immunoprecipitation-Grade [Antibodies]
Principal investigator: Keith Kropp
Organization: Aptakon
Project start date: Sept. 22, 2010
Project end date: Jan. 31, 2011
NIH institute: NHGRI
FY 2010 funding amount: $97,500


Receptor/Ligand Signals for Ovarian Follicular Angiogenesis

Principal investigator: Leon Spicer
Organization: Oklahoma State University
Project start date: Sept. 22, 2010
Project end date: Aug. 31, 2013
NIH institute: NICHD
FY 2010 funding amount: $352, 346


Exercise and Energy Balance: Role of Hypothalamic Transthyretin

Principal investigator: Sheng Bi
Organization: Johns Hopkins University
Project start date: Sept. 23, 2010
Project end date: Aug. 31, 2014
NIH institute: NIDDK
FY 2010 funding amount: $423,200


Transcriptional Control of Collective Cell Migration
Principal investigator: Lionel Christaen
Organization: New York University
Project start date: Sept. 23, 2010
Project end date: Aug. 31, 2015
NIH institute: NIGMS
FY 2010 funding amount: $299,030


Identification of Antigens for Anti-HIV Broadly Neutralizing Responses

Principal investigator: Steven Zeichner
Organization: Children's Research Institute
Project start date: Sept. 24, 2010
Project end date: Aug. 31, 2014
NIH institute: NIAID
FY 2010 funding amount: $585,343


Identification of Genes and Compounds that Control Beta Cell Replication
Principal investigator: Douglas Melton
Organization: Harvard University
Project start date: Sept. 25, 2010
Project end date: Aug. 31, 2013
NIH institute: Office of the Director
FY 2010 funding amount: $4,395,697


Pharmacologic Treatment of Mitochondrial Complex I Dysfunction in C. Elegans
Principal investigator: Marni Falk
Organization: Children's Hospital of Philadelphia
Project start date: Sept. 27, 2010
Project end date: May 31, 2015
NIH institute: NICHD
FY 2010 funding amount: $414,256


Project 1: Mechanisms of Nanomaterial-Cell Interactions
Principal investigator: Brian Thrall
Organization: Battelle Pacific Northwest Laboratories
Project start date: Sept. 28, 2010
Project end date: April 30, 2015
NIH institute: NIEHS
FY 2010 funding amount: $564,431


U1 Adaptor: Dendrimer Silencing on BCL2 for Tumor Suppression
Principal investigator: Rafal Goraczniak
Organization: Silagene
Project start date: Sept. 29, 2010
Project end date: Feb. 28, 2010
NIH institute: NCI
FY 2010 funding amount: $189,496

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Biosignature of the Endometrium in Women with Endometriosis
Principal investigator: Ruo-Pan Huang
Organization: RayBiotech
Project start date: Sept. 29, 2010
Project end date: Aug. 31, 2011
NIH institute: NCRR
FY 2010 funding amount: $100,000


MicroRNA Profiles of TN Breast Cancer to Define Subgroups and Targets for Therapy
Principal investigator: Kay Huebner
Organization: Ohio State University
Project start date: Sept. 30, 2010
Project end date: July 31, 2015
NIH institute: NCI
FY 2010 awarded amount: $548,311


Identifying the Spectrum of Genetic Alterations in High Risk ALL
Principal investigator: Charles Mullighan
Organization: St. Jude Children's Research Hospital
Project start date: Sept. 30, 2010
Project end date: Sept. 29, 2013
NIH institute: NCI
FY 2010 funding amount: $1,573,220


Mechanisms of the Response to Hydrogen Sulfide

Principal investigator: Dana Miller
Organization: University of Washington
Project start date: Sept. 30, 2010
Project end date: Aug. 31, 2013
NIH institute: NIA
FY 2010 funding amount: $249,000


A Drosophila Model for Williams Syndrome Cognitive Processing

Principal investigator: Ralph Greenspan
Organization: University of California San Diego
Project start date: Sept. 30, 2010
Project end date: Sept. 29, 2011
NIH institute: NEI
FY 2010 funding amount: $245,038


Roles of microRNAs During Vertebrate Brain Morphogenesis

Principal investigator: Carter Takacs
Organization: Yale University
Project start date: Nov. 1, 2010
Project end date: March 31, 2013
NIH institute: NICHD
FY 2010 funding amount: $50,474


Population Genetic Studies of Human Copy-Number Polymorphisms

Principal investigator: Catarina Campbell
Organization: University of Washington
Project start date: Nov. 16, 2010
Project end date: Nov. 15, 2012
NIH institute: NHGRI
FY 2010 funding amount: $52,154


Studies of Antibody Diversity and Genome Stability

Principal investigator: Yee Wu
Organization: UK Medical Research Council Laboratory of Molecular Biology
Project start date: Nov. 24, 2010
Project end date: Nov. 23, 2013
NIH institute: NIAID
FY 2010 funding amount: $39,756


Companion Diagnostics for ALK Mutations

Principal investigator: David Hout
Organization: Insight Genetics
Project start date: N/A
Project end date: N/A
NIH institute: NCI
FY 2010 funding amount: $200,000


TAS::75 0849::TAS Small Business Innovative Research Topic 283

Principal investigator: Bruce Seligmann
Organization: High Throughput Genomics
Project start date: N/A
Project end date: N/A
NIH Institute: NCI
FY 2010 funding amount: $149,967


TAS::75 0849::TAS
Principal investigator: Swapnajit Chakravarty
Organization: Omega Optics
Project start date: N/A
Project end date: N/A
NIH Institute: NCI
FY 2010 funding amount: $200,000

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.