Skip to main content
Premium Trial:

Request an Annual Quote

Fluidigm, Aueron Laboratories, Pall Corp.

Fluidigm of South San Francisco, Calif., has received European Patent No. 1882189, “Analysis engine and database for manipulating parameters for fluidic systems on a chip.” The patent claims a system for managing workflow related to processing of one or more microfluidic devices. The system includes a processor device, a first database coupled to the processor device, and one or more process designs provided within a portion of the first database. The system further includes an image acquisition device coupled to the processor device.

Aueron Laboratories of Yonkers, NY, has received US Patent No. 7,326,575, “Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization.” The patent claims methods for the detection of one or more mRNA transcripts in paraffin-embedded tissue by mRNA liberation in fixed-treated tissue. This method includes treating the tissue with ammonia-ethanol and sodium borohydride combined with pressure cooking of the tissue. The chemical treatments reduce the tissue autofluorescence and the physical treatments overcome the interference created by the fixation-induced chemical bonds. The methods of the patent can be utilized to identify a plurality of mRNA transcripts in a microarray format.

Pall Corp. of East Hills, NY, has received US Patent No. 7,326,776, “Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays.” The patent claims a method for the separation of biological substances from a sample by: a) contacting a solid substrate that includes a solid support with a biological substance; b) adsorbing the biological substance to the solid substrate; c) washing the solid substrate obtained with an equilibration buffer; and d) adjusting the pH so that the biological substance desorbs from the solid substrate.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.