Skip to main content

Expression Diagnostics, BioMicro Systems

Premium
Expression Diagnostics of South San Francisco, Calif., has received US Patent No. 7,235,358, “Methods and compositions for diagnosing and monitoring transplant rejection.” The patent describes methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient. According to the patent’s abstract, the gene expression system used for diagnosis may be a candidate library, a diagnostic agent, a diagnostic oligonucleotide set or a diagnostic probe set. The gene expression system may also be immobilized on an array, such as a chip array, a plate array, a bead array, a pin array, a membrane array, a solid surface array, a liquid array, an oligonucleotide array, a polynucleotide array, a cDNA array, or a microfilter plate.
 

 
BioMicro Systems of Salt Lake City has received US Patent No. 7,235,400, “Laminated microarray interface device.” The patent claims a device for forming a low-volume reaction chamber on a substrate such as a microarray slide as well as its method of use. According to the patent, the reaction chamber forming device has an adhesive laminate design that permits it to be manufactured as a disposable device. The patent also describes pneumatically actuatable mixing bladders, which can be inflated or deflated to produce deflection of a wall of the reaction chamber in and out with respect to the reaction chamber to generate movement and mixing of fluid within the reaction chamber in, for example, a hybridization station.

The Scan

Pfizer-BioNTech Seek Full Vaccine Approval

According to the New York Times, Pfizer and BioNTech are seeking full US Food and Drug Administration approval for their SARS-CoV-2 vaccine.

Viral Integration Study Critiqued

Science writes that a paper reporting that SARS-CoV-2 can occasionally integrate into the host genome is drawing criticism.

Giraffe Species Debate

The Scientist reports that a new analysis aiming to end the discussion of how many giraffe species there are has only continued it.

Science Papers Examine Factors Shaping SARS-CoV-2 Spread, Give Insight Into Bacterial Evolution

In Science this week: genomic analysis points to role of human behavior in SARS-CoV-2 spread, and more.