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ExonHit Therapeutics, Agilent, Evident Technologies, Spotfire

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ExonHit Therapeutics last week added Nuclear Receptor and Co-Regulator arrays to its SpliceArray Service business unit. Launched in February, the SpliceArray Service provides users with ExonHit's splice variant content, probe design, and customized analysis with Agilent's microarray platform.

The Paris -based firm said that the global pharmaceutical market for drugs targeting nuclear receptors is estimated to be around $40 billion and the new arrays will aid in drug discovery. The initial rollout of the service included Ion-Channel and GPCR arrays.


Evident Technologies last week released its second-generation Type 2 EviTag luminescent label. The Troy, NY-based company claims the T2 EviTag provides increased flexibility, wider applications and testing cost reduction in bioassays and other types of life science research.

Evident's EviTag technology incorporates the company's EviDot quantum dots, which are semiconductor nanocrystals coated with a variety of patented, water-stabilizing surface treatments. The new product complements Evident's Type 1 EviTags which the company markets as a fluorescent label.


Spotfire last month launched DecisionSite 8.1, the latest version of its visual data analytics platform. The company claims the newer version of DecisionSite offers user greater analysis across the R&D organization through faster, more flexible data access; enhanced data analysis features; expanded results-sharing capabilities; and improved security and administration.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.