NEW YORK (GenomeWeb) – A set of studies published online today in Nature offers a look at similarities and differences detected in the regulatory machinery over time and across organisms.

By drawing on data generated through the ENCODE and modENCODE projects, members of those consortia considered the interplay between gene expression profiles, chromatin network arrangements, and other regulatory features in human, fruit fly, and Caenorhabditis elegans worm tissues — efforts that revealed extensive conservation for some aspects of the regulatory process.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.