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Daniel Bradbury, John Stuelpnagel, Illumina, Agilent Technologies, Expression Analysis, ExonHit Therapeutics

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Daniel Bradbury and John Stuelpnagel have been reelected to Illumina's board of directors, following the company's annual meeting of stockholders held in San Diego last week, the company said.

Bradbury serves as chief operating officer of Amylin Pharmaceuticals, and Stuelpnagel is senior vice president and COO of Illumina.

New Product Watch

Illumina last week began shipping its Sentrix Human-1 Genotyping BeadChip platform for SNP genotyping. The chip is powered by the company's Infinium assay, and can interrogate more than 100,000 SNP loci per sample, Illumina said.

The Sentrix Human-1 BeadChip and Infinium assay are part of a genotyping package that includes reagents, a BeadArray Reader, allele-calling software, and installation and training. The company said that existing BeadStation system customers, will require minor software and equipment upgrades to use the new platform.


Agilent Technologies last week released its Zebrafish Oligo Microarray and Mouse Development Oligo Microarray 44K.

The Zebrafish array contains 21,495 probes that represent genes from public databases like RefSeq and Unigene, Agilent said, as well as QC probes for monitoring experimental variations.

Agilent's Mouse Development Oligo Microarray 44K contains 44,041 probes representing mouse genes and transcripts from the National Institute of Aging Mouse Gene Index. The company recommends the tool for the study of stem cells and developmental biology.


Expression Analysis last week introduced its Globin Reduction Service, an enhancement of the company's RNA isolation services, which reduces interference in globin mRNAs to increase the sensitivity of detection of microarray transcripts in blood, the company said.

The service can be performed on whole blood from PreAnalytiX PAXgene Blood RNA Tubes or Applied Biosystems Tempus Blood RNA Tubes, according to the microarray genetics testing and analysis organization.


ExonHit Therapeutics last week made available its Cytokine SpliceArrays through the company's SpliceArray Service business unit.

The company released splice-variant arrays for the gene families connected with apoptosis last month, and has also made arrays for nuclear/co-regulators, GPCR, and ion channel families available since the service launched last February.

ExonHit said that the newest array, which is printed by Agilent Technologies, can be used for research into immunity, inflammation, and hematopoiesis. Arrays for other gene families will be made available in coming months, the company said.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.