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Daniel Bradbury, John Stuelpnagel, Illumina, Agilent Technologies, Expression Analysis, ExonHit Therapeutics

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Daniel Bradbury and John Stuelpnagel have been reelected to Illumina's board of directors, following the company's annual meeting of stockholders held in San Diego last week, the company said.

Bradbury serves as chief operating officer of Amylin Pharmaceuticals, and Stuelpnagel is senior vice president and COO of Illumina.

New Product Watch

Illumina last week began shipping its Sentrix Human-1 Genotyping BeadChip platform for SNP genotyping. The chip is powered by the company's Infinium assay, and can interrogate more than 100,000 SNP loci per sample, Illumina said.

The Sentrix Human-1 BeadChip and Infinium assay are part of a genotyping package that includes reagents, a BeadArray Reader, allele-calling software, and installation and training. The company said that existing BeadStation system customers, will require minor software and equipment upgrades to use the new platform.


Agilent Technologies last week released its Zebrafish Oligo Microarray and Mouse Development Oligo Microarray 44K.

The Zebrafish array contains 21,495 probes that represent genes from public databases like RefSeq and Unigene, Agilent said, as well as QC probes for monitoring experimental variations.

Agilent's Mouse Development Oligo Microarray 44K contains 44,041 probes representing mouse genes and transcripts from the National Institute of Aging Mouse Gene Index. The company recommends the tool for the study of stem cells and developmental biology.


Expression Analysis last week introduced its Globin Reduction Service, an enhancement of the company's RNA isolation services, which reduces interference in globin mRNAs to increase the sensitivity of detection of microarray transcripts in blood, the company said.

The service can be performed on whole blood from PreAnalytiX PAXgene Blood RNA Tubes or Applied Biosystems Tempus Blood RNA Tubes, according to the microarray genetics testing and analysis organization.


ExonHit Therapeutics last week made available its Cytokine SpliceArrays through the company's SpliceArray Service business unit.

The company released splice-variant arrays for the gene families connected with apoptosis last month, and has also made arrays for nuclear/co-regulators, GPCR, and ion channel families available since the service launched last February.

ExonHit said that the newest array, which is printed by Agilent Technologies, can be used for research into immunity, inflammation, and hematopoiesis. Arrays for other gene families will be made available in coming months, the company said.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.