CGH+SNP or just SNP? Geneticists who use microarrays for constitutional and cancer cytogenetics have never had so many choices. Four large vendors currently serve the market, and a number of other players sell a variety of designs optimized for different indications or communities.

But according to some longtime users of chromosomal microarrays, the decision of what platform to use often has more to do with the circumstances in which one adopts the technology.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.