Skip to main content
Premium Trial:

Request an Annual Quote

Cuno Inc., Industrial Technology Research Institute, Affymetrix, Hitachi Software Engineering

Premium

Cuno Inc. of Meriden, Conn., received US Patent No. 6,734,012, "Low fluorescence nylon/glass composites for micro-analytical diagnostic applications." The patent covers a method for constructing composite microarray non-luminescent slides with a microporous membrane attached by covalent bonding through a surface treatment to a substrate. Apparatus and methods for fabricating non-luminescent composite microarray slides are also disclosed.


Industrial Technology Research Institute of Taiwan received US Patent No. 6,733,894 "High-density functional slide and preparation method thereof." The patent covers a method for preparing a high-density functional slide by coating a sol-gel containing amine-group bearing silanes and a solution containing polyaldehyde groups onto an organic or inorganic substrate, respectively. The resulting slide is useful in the preparation of highly homogeneous functional-group slides and the high-density and high-efficiency bio-chip/microarray.


Affymetrix received US Patent No. 6,733,969, "Expression monitoring for gene function identification." This invention provides methods for mapping the regulatory relationship among genes by massive parallel monitoring of gene expression. Mutations in the upstream regulatory genes are detected by monitoring the change in downstream gene expression. In addition, regulatory function of a target gene can be determined by monitoring the expression of a large number of downstream genes. The invention also provides specific embodiments for detecting p53 functional homozygous and heterozygous mutations and for determining the function of p53 mutations.


Hitachi Software Engineering received US Patent No. 6,733,968, "Microarray, method for producing the same, and method for correcting inter-pin spotting amount error of the same." The patent covers a system that corrects inter-pin spotting errors resulting from microarraying production. In microarray production, samples are immobilized on a microarray support using all pins as controls for correcting the inter-pin spotting amount errors. After the microarray experiments, luminescent intensities of the samples used as control spots for correcting the inter-pin spotting amount errors are measured and used to obtain correction parameters for the inter-pin spotting amount errors. These parameters are used to correct luminescent intensities of other samples.

 

The Scan

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.

Study Points to Benefits of Local Consolidative Therapy, Targeted Treatments in Cancer Care

In JCO Precision Oncology, researchers report that local consolidative therapy combined with molecularly targeted treatments could improve survival for some lung cancer patients.

Genetic Variants That Lower LDL Cholesterol Linked to Reduced Heart Disease Risk

Rare variants in two genes that lower LDL cholesterol are also associated with a decreased risk of coronary heart disease, according to a new JAMA Cardiology study.

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.