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CombiMatrix, Matrix Technologies, Epoch Biosciences, VizX Labs

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CombiMatrix announced the introduction of two new CustomArray catalog products — the Human Drug Metabolism Array and the Human Toxicology Array. The drug metabolism array will enable researchers to screen a panel of genes and splice variants known to be important for the pharmacokinetics and metabolism of drugs, according to the firm. The array, which is based on the most recent available information on genes controlling drug metabolism, provides nearly complete coverage of the cytochrome p450 gene family, UDP-glucuronosyl-transferases, glutathione-transferases, sulfo-transferases, and N-acetyl-transferases, CombiMatrix said. The new array is the first in a series of catalog arrays it expects to introduce over the coming months. The Human Toxicology Array contains more than 12,000 probes to genes selected from scientific literature and public databases and is designed for detecting changes in gene expression that indicate a toxic or stress-related response.


Matrix Technologies has announced the availability of NanoPin ceramic pins for microarraying. The NanoPin improves spot uniformity and efficiency of sample utilization, shortens printing run times and eliminates pre-blotting with most print buffers, according to the company. The NanoPins range from 30 to 80pLs and can be used for spotting proteins and DNA.


Epoch Biosciences announced last week the introduction of 21 MGB Eclipse Detection Reagents, analyte specific reagents marking the firm’s foray into the molecular diagnostics market. The reagents are targeted to the infectious diseases, inherited diseases and cancer diagnostic markets. The introduction of the new reagents is part of Epoch’s efforts to diversify its sources of revenue and shift more of its product mix to end-user sales, the company said.


VizX Labs rolled out the GeneSifter Core Edition microarray analysis system for use in microarray core facilities, providing the facilities with computing and storage resources on off-site secure servers. The new product adds flexible administrative tools to its GeneSifter Lab Edition that allow core facilities to provide and manage GeneSifter accounts for their clients, according to the firm.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.