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Clarification: Aug 6, 2003

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CLARIFICATION — Applied Biosystems is not beta-testing its Expression Array system with Immune Tolerance Networks, a collaborative research effort headquartered at the University of California, San Francisco, the company said last week. The gene expression work Mike Hunkapiller, president of ABI, mentioned during Applera’s fourth-quarter conference call with analysts in regard to Immune Tolerance Network, is the company’s traditional gene-expression analysis conducted with its Taqman chemistry and primers, and Realtime PCR, a company spokeswoman told BioArray News. The company, which declined comment and details on its promised microarray platform, is not releasing the names of beta testers of its microarray platform and will not have any further comment on the platform until it is rolled out, the spokeswoman said.

 

CLARIFICATION — In last week’s report, the mention of Affymetrix Research Lab prototype array capable of handling over 60 million fragments of DNA [Affymetrix annual report, page 14] describes a whole-wafer product, rather than a single chip cut from a wafer, an Affymetrix spokesman told BioArray News.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.