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Chemicon International, Insightful

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Chemicon International of Temecula, Calif., has launched its ATA100 Advanced Tissue Arrayer. The instrument, built in collaboration with Advanced EDM Automation, is designed to build custom tissue microarrays from paraffin blocks containing multiple tissue samples. It contains a microscope, an illuminated reference slide stage, a donor and a recipient block station.

Statistics company Insightful of Seattle has released Insightful ArrayAnalyzer, a microarray data analysis tool. Based on S-PLUS and StatServer, ArrayAnalyzer uses a mapped workflow interface that guides the user through the analysis process, including data uploading, normalization, differential expression testing, and annotation. It is compatible both with Affymetrix and cDNA arrays and takes advantage of S-PLUS’s Web Graphlets to show tabular and graphical summaries of differentially expressed genes.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.