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Cepheid Wins $3.3M NIAID Grant to Further Develop PCR-Based TB Dx

NEW YORK (GenomeWeb News) – Cepheid today said it has received a $3.3-million Small Business Technology Transfer grant from the National Institute of Allergy and Infectious Disease to further develop its Mycobacterium tuberculosis diagnostic.
 
Cepheid and academic partners at the University of Medicine and Dentistry of New Jersey have worked together to develop a PCR cartridge that can detect M. tuberculosis and predict its resistance to drugs in about one hour.
 
The new grant will “complement these efforts by focusing on development of sample collection devices and on development of proprietary nucleic acid dyes, quenchers, interpretive software and other technologies associated with commercial implementation of a 6-color GeneXpert system,” Cepheid said in a statement.
 
As GenomeWeb News reported last week, the US Food and Drug Administration said CLIA labs can use another of Cepheid’s tests, the Xpert Group B Streptococcus diagnostic, making it the first amplified molecular diagnostic using real-time PCR to receive the moderate complexity CLIA categorization. diagnostic, making it the first amplified molecular diagnostic using real-time PCR to receive the moderate complexity CLIA categorization.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.