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Canon Kabushiki Kaisha, Zyomyx, Biolog


Canon Kabushiki Kaisha of Tokyo earned US Patent No. 6,476,215, “Ink jet method of spotting a probe and manufacturing a probe array.” The patent covers a method of spotting a probe densely and efficiently on a surface of a solid support. A liquid is attached as droplets by ink jet to form spots containing the probe.

Zyomyx of Hayward, Calif., was awarded US Patent No. 6,475,809, “Protein arrays for high-throughput screening.” The patent covers a design for protein arrays and protein-coated substrates where different members of a single protein family may be immobilized on the protein-coated substrate or array for parallel, high-throughput screening. The company also earned US Patent No. 6,475,808, “Arrays of proteins and methods of use thereof.” The patent covers arrays of organic thinfilms on a substrate surface holding different members of a single protein family.

Biolog of Hayward, Calif., has earned US Patent No. 6,387, 651, the company said this week. The patent was granted for comparative phenotypic analysis of two or more microorganisms, using a number of substrates within a microwell device. The patent covers methods and compositions for phenotypic analysis of eukaryotic as well as prokaryotic cells.

The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.