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BioArray Funding Update: Recent NSF Awards in Microarray Technology

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Innovative Protein Microarrays
Start Date:
Date: July 1, 2002
Expires: December 31, 2002
Estimated total amount: $99,978
Investigator: Andrzej K. Drukier
Sponsor: BioTraces

Small Business Innovation Phase I project to perform quantitation of proteins on antibody arrays using a method known as Multi Photon Detection technique (MPD). The company plans to initially create a cytokine array, and aim “to create an immunoassay based protein chip for the concurrent measurement of all the cytokines down to the level of a few zeptomole/ sample, to implement improved P-chip designs using peptide nucleic acid linkers, and to study the levels of cytokines in cell cultures and human samples.” Using the arrays, the company, based in Herndon, Va., hopes to correlate protein expression patterns with disease states.

• Patterned Substrates for Biochips
Start Date: July 1, 2002
Expires: December 31, 2002
Estimated total amount: $100,000
Investigator: Anoop Agrawal
Sponsor: ENKI

The goal of this Small Business Innovation Research Phase 1 Project is to develop microarrays for genomics and diagnostics made of sol-gel coatings and microstructures. The substrate, according to the grant award, “will allow higher density arrays and higher signal/noise ratio from each of the array elements.” ENKI, of Tucson, Ariz., plans to develop the microarrays for use in agriculture and healthcare.

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