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BioArray Briefs: Jun 28, 2002


LumiCyte Signs $30 Million Marketing, Distribution Agreement with Shimadzu

Protein profiling biochip company LumiCyte of Fremont, Calif., has signed an exclusive five-year agreement with Japanese trading giant Shimadzu to market and distribute LumiCyte’s SELDI-based protein mapping services. The agreement, valued at more than $30 million, also includes a multi-million dollar investment by Shimadzu, based in Kyoto. “We believe their distinguished history and leadership in clinical proteomics and bioinformatics will enable our customers in Japan to rapidly implement the best solutions available for drug development,” said Shigehiko Hattori, managing director for Shimadzu, in a statement. LumiCyte’s biochips are based on surface enhanced laser desorption ionization, or SELDI technology, a chip-based system similar to mass spectrometry. Ciphergen, also of Fremont, Calif., markets these chips as its “ProteinChip” system, while Lumicyte uses them in-house to do protein profiling as a service for customers. The companies are currently involved in a lawsuit in which Ciphergen sued over the rights to this SELDI technology, and alleged that LumiCyte CEO William Hutchens, the former chief scientific officer of Ciphergen, misappropriated trade secrets. The trial is slated for January 2003.


BioForce Gets $250,000 SBIR Grant

Nanoarray maker BioForce Nanosciences of Ames, Iowa, has been awarded a $250,000 Phase I Small Business Innovation Research grant from the National Institutes of Health to develop an ultra-miniaturized biological warfare agent detection system. The company will use the grant to create a nanoarray that can detect simulants of biological warfare agents. Future studies will develop a comprehensive nanoarray panel to detect several known biological warfare agents. “We are working to advance pathogen detection systems,” stated Curtis Mosher, principal investigator on the project, “to increase the speed and accuracy of detection and to reduce public concerns on biological warfare threats.”

The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.