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BD Biosciences Clontech, GE Healthcare, Koada Technology, Stanford University


BD Biosciences Clontech has released a new DNA amplification product called BD Taq Full DNA Polymerase. The enzyme is a full-length recombinant version of the Thermus aquaticus strain YT1 DNA polymerase. It can amplify DNA from any template and is recommended by the company for any general PCR amplification procedure. The product claims to be highly efficient and sensitive, allowing scientists to use less enzyme and template in each reaction. It is also available with a hot start antibody.

GE Healthcare has added a new array to its CodeLink series, the ADME Rat 16-Assay bioarray. The gene-expression array has a multi-assay chamber that allows up to 16 samples to be processed in parallel on every slide. Each slide has 16 arrays, containing over 1,200 oligonucleotide probes each targeting rat genes involved in drug absorption, distribution, metabolism, and excretion processes. This is the first CodeLink catalog product that offers 16 assays per slide. It is compatible with existing CodeLink instruments, reagents, and accessories.

GE Healthcare has also upgraded its CodeLink Expression Analysis Software. Version 4.1 is now available and compatible with the new bioarray.

Koada Technology has released Koadarray V2.4, a software package that it claims offers automated analysis and quantification of array images. The Scottish firm said that that V2.4 eliminates user intervention in microarray analysis, making the interpretation of data more reliable and objective.

Researchers at Stanford University released an updated version of Java Treeview, a cross platform, open-source program for microarray data visualization, last week.

The Scan

Study Follows Consequences of Early Confirmatory Trials for Accelerated Approval Indications

Time to traditional approval or withdrawal was shorter when confirmatory trials started prior to accelerated approval, though overall regulatory outcomes remained similar, a JAMA study finds.

Sequencing Study Leads to Vaccine Target in Bacteria Behind Neonatal Meningitis

Researchers eBioMedicine track down potential vaccine targets with transposon sequencing on mutant bacteria causing neonatal meningitis in mouse models of the disease.

Multiple Myeloma Progression Influenced by Immune Microenvironment Expression

Researchers in NPJ Genomic Medicine compare RNA sequencing profiles of 102,207 individual cells in bone marrow samples from 18 individuals with rapid or non-progressing multiple myeloma.

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.