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Axon Instruments, NuGen Technologies, Affymetrix, Eppendorf, Linden Bioscience


Axon Instruments is preparing to release an upgrade of its 4200A microarray scanner, the 4200AL model, which will add a 36-slide magazine for autoloading, scanning, and analyzing microarray slide images. The scanner, the company said at the Chips to Hits conference in Boston last week, will have a flexible batch and slide configuration that will allow scanning and analysis parameters for individual slides, sets of slides, or full batches. Pricing details were not disclosed. The autoloader can process a full batch in two colors at 10-micron resolution in five hours, a company spokesman told BioArray News.

NuGen Technologies previewed its Ovation RNA amplification and biotin labeling system, optimized for use on Affymetrix microarrays at Chips to Hits last week. The product, which generates microgram quantities of cDNA using one protocol for all samples, will be commercially available in 2004.

Eppendorf introduced its DualChip low-density DNA microarray at Chips to Hits last week. The array contains a gasket over a barcoded standard format glass slide that divides an array into two parts. The company is offering the product with content for: rat G protein-coupled receptors, human and rat hepato for toxicology and drug development; human aging (240 genes); and human general (202 genes) in its initial foray into offering content.

Linden Bioscience this week introduced its Expression Snapshot mRNA archiving kit, an archival double-stranded DNA representation of original RNA samples that can be stored and retranscribed repeatedly over several months. The kit includes all of the reagents needed to perform the Eberwine mRNA amplification procedure on the samples, including reverse transcription, second strand DNA synthesis, and T7 RNA polymerase transcription.


The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.