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Aviva Systems Biology, Applied Biosystems, Agilent


Aviva Systems Biology last week launched its ChIP-GLAS system, which the company claims can simultaneously detect 20,000 human promoters from a single sample, and should be useful for researchers conducting gene transcription studies.

The San Diego-based company said the first stage launch of the system includes both 10K and 20K ChIP-GLAS microarrays, as well as a supporting kit for users.

Applied Biosystems last week introduced its Advanced Gene Expression Service Provider Program to encourage service providers to use its Expression Array System and TaqMan assays for gene expression-analysis offerings.

The company said it is offering a product bundle around its Expression Array System — which includes human, rat, and mouse arrays, as well as technical and promotional support, and options for including additional products such as TaqMan assays and RT-PCR systems.

Agilent this week released its Literature Search tool, an automated tool for the multidisciplinary study of biological systems. The tool is available as a free plug-in to Cytoscape 2.1, an open-source bioinformatics platform that enables researchers to form a visual map of complex biological networks, increasing their understanding of molecular pathways and the biological causes of disease.

According to Agilent, the tool searches for and extracts information from multiple textual databases, such as those of the US Patent Office and the National Center for Biotechnology Information. The plug-in pulls information from these sources and represents it within Cytoscape as a map of the relationships between the biological entities, such as genes and proteins for the users convenience.

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.