Signature NPM1 Mutations is made available on the Luminex 100 IS or 200 System using a liquid bead array method. According to the company, the liquid bead array format provides “comprehensive information in a single well, providing efficiency and cost benefits to the laboratory.”
Asuragen: Aug 19, 2008
Asuragen this week launched Signature NPM1 Mutations, a multiplex, reverse-transcription PCR assay that enables the combined detection of mutations A, B, and D in exon 12 of the nucleophosmin (NPM1) gene.
According to Asuragen, the assay is designed to detect NPM1 mutant transcripts in total RNA isolated from cell line, whole blood, and bone marrow specimens. NPM1 has been reported to be one of the most commonly mutated genes in acute myeloid leukemia.