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Aspira Biosystems, Genzyme Molecular Oncology


Aspira Biosystems of San Francisco has received US Patent No. 6,458,599, “Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules.” The patent claims broad methods of making imprint compositions capable of capturing macromolecules of interest. The invention encompasses solidifying a fluidic material, such as a mixture of polymers, which form shaped cavities in the presence of a template molecule that corresponds to a portion of the macromolecule. Once the polymers are solidified, the template molecules are removed, producing cavities that are capable of capturing the target macromolecule. Under the trade name ProteinPrint, Aspira is applying this technology to make arrays of protein capture agents for detecting specific proteins in biological samples.

Genzyme Molecular Oncology of Framingham, Mass., has received Japanese Patent No. 3,334,806. According to the company, the patent covers the methodology by which SAGE (Serial Analysis of Gene Expression) identifies and measures gene expression. Genzyme received a US patent covering SAGE in 1997.

The Scan

Dropped Charges

The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal.

More Kids

The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children.

PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS

In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more.

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.