By Justin Petrone

Longtime array rivals Affymetrix and Illumina last week introduced new chips targeting the exome, exonic variants in the protein-coding regions of the human genome.

Both firms believe that their respective exon arrays, scheduled to launch by the first quarter of 2012, will provide users with the ability to validate such variants in large sample numbers in a "fast and economical way."

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

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