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Ariadne Genomics, Bayer, Integragen, Illumina, Genomatix

Ariadne's European Facility Opens in Madrid, Spain; Bayer Renews License
Ariadne Genomics on June 1 opened an office in Madrid to manage European sales and marketing and to support and train clients, the company said last week.
It is currently hiring sales and support staff for the office. Also, it plans to relocate a US-based lead-application scientist to the new facility, after which time that facility itself will be moved, company spokeswoman Natalia Alexandrova wrote in an e-mail to BioArray News’ sister publication GenomeWeb Daily News.  
Ariadne also said that former Integromics CEO Olivier Brun will run the European operations.
Separately, Ariadne last week said that Bayer HealthCare has renewed and expanded a licensing agreement that allows it to use the company’s Pathway Studio through 2010 for toxicology studies and microarray data analysis.
The Ariadne data-mining software is used to analyze pathways and signaling networks, and to interpret microarray data, the company said.
Ariadne also said it is developing a MedScan toxicology module that holds knowledge of small molecules and their interactions with cells and proteins, which Bayer HealthCare will use in its research.
Financial terms of the agreement were not released.

Illumina Certifies Integragen for GoldenGate, Infinium Genotyping
Integragen has received certification as a service provider for Illumina's GoldenGate and Infinium genotyping technologies, Illumina said last week.
Illumina said the GoldenGate assay is designed for DNA methylation profiling, and offers a combination of high sample throughput, high multiplexing, and single-site CpG resolution. The Infinium BeadArray is used for custom SNP assays, and offers multi-sample BeadChip formats and high-density architecture, the company said.
Integragen, based in Evry, France, has already supplied the Illumina technology to study the loss of heterozygosity in liver tumors at the Human Polymorphism Study Center in Paris, Illumina said.
Illumina said that its certification process includes minimum data generation, data certification, and an on-site audit of the labs and processes.

German Software Shop Genomatix Opening US Subsidiary in Michigan
Munich, Germany-based Genomatix Software last week said it plans to open a US subsidiary called Genomatix Software, Inc., in Ann Arbor, Mich.
Genomatix said the new subsidiary, which was incorporated May 14, will sell, support, and market the company’s software products for microarray analysis, regulatory network and pathway mining, and sequence-level promoter analysis.
The subsidiary will also house a Genomatix Training Academy that will offer “university-like courses” related to its software offerings, the firm said.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.