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Applied Gene Technologies, The University of Arizona, Nanogen

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Applied Gene Technologies of San Diego has received US Patent Number 6,380,377, “Nucleic acid hairpin probes and uses thereof.” The patent describes hairpin oligonucleotide structures, and arrays of these probes on a solid substrate, as well as methods for hybridization using these probes.

 

The University of Arizona has received US Patent Number 6,379,970, “Analysis of differential protein expression.” The patent covers a method of detecting peptides present in different amounts in different samples.

 

Nanogen has received US Patent Number 6,379,897, “Methods for gene expression monitoring on electronic microarrays.” The invention involves gene expression monitoring methods using microelectronic microarrays. The invention involves amplification producing amplicons of a specific length, and electronic primer-based methods for detecting their levels.

The Scan

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.

Study Offers Insights Into Role of Structural Variants in Cancer

A new study in Nature using cell lines shows that structural variants can enable oncogene activation.

Computer Model Uses Genetics, Health Data to Predict Mental Disorders

A new model in JAMA Psychiatry finds combining genetic and health record data can predict a mental disorder diagnosis before one is made clinically.

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.