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Applied Biosystems, Parallel Synthesis Technologies


The new expression analysis system launched by Applied Biosystems will be marketed as the Applied Biosystems 1700 Chemiluminescent Microarray Analyzer. The product will sell at a list price of $177,000, according to the company. The company’s initial product for this platform, a whole-human-genome single microarray, will list for $890.

Parallel Synthesis Technologies of Santa Clara, Calif., this week introduced its Silicon Microarray contact printing technology for spotting DNA and protein microarrays. The four-year-old company machines its spotting pins from single-crystal silicon wafers using semiconductor-manufacturing techniques. The product line can spot directly from a 1,536-well source plate, and can print with 192 pins simultaneously, performing 400 spots per fill of 100 nanoliters. Print tip sizes range from 50x50 to 200x200 microns enabling the creation of spots ranging from 75 to 250 micrometers in diameter. The company has successfully test- printed materials such as proteins, lipids, and whole cell lysates.

The Scan

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.

Seagull Microbiome Altered by Microplastic Exposure

The overall diversity and the composition at gut microbiome sites appear to coincide with microplastic exposure and ingestion in two wild bird species, according to a new Nature Ecology and Evolution study.

Study Traces Bladder Cancer Risk Contributors in Organ Transplant Recipients

In eLife, genome and transcriptome sequencing reveal mutation signatures, recurrent somatic mutations, and risky virus sequences in bladder cancers occurring in transplant recipients.

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.