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Applied Biosystems, ArrayExpress, Ensembl

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Applied Biosystems has launched its 7900HT Fast Real-Time PCR System offered in a traditional 96-well format. The firm said that the system reduces real-time PCR thermal cycling times up to four-fold compared to standard real-time PCR systems. The platform is capable of providing PCR results in approximately 35 minutes, compared to roughly two hours on existing 96-well format real-time PCR systems, according to ABI.


EBI’s ArrayExpress team has released Tab2MAGE 1.0, a spreadsheet-parsing and MAGE-ML generation tool, at http://tab2mage.sourceforge.net/. Tab2MAGE currently includes two tools: the tab2mage.pl script, and a file-checking script, expt_check.pl. With these scripts, users can perform an initial data file validation against an array design, and then generate MAGE-ML using these data files alongside a separate spreadsheet providing MIAME-compliant sample annotation.


Ensembl release 25 is now available at http://www.ensembl.org. There are no new assemblies in the release.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.