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Apogent Discoveries, Silicon Genetics


Apogent Discoveries of Hudson, NH, is introducing MicroSpot C ceramic pins for printing microarrays. The pins are designed for use with the company’s MicroGrid arrayer. The product will produce more spots per source visit and requires no pre-blotting. It can be used for printing proteins, amino acids, peptides, oligos, and nucleic acids. Apogent says the chemically inert pins have been tested with up to 1 million hits against a glass slide without deformation or changes to the morphology of the spots.


Silicon Genetics has released GeneSpring 5.1 and GeNet 3.1. Among other new features, the company’s GeneSpring gene expression analysis software now includes a visual scripted editor and creation tool that allows users to automate a series of analytical tasks using a set of drag-and-drop icons.

The GeNet enterprise-scale gene expression data analysis and management system now offers a sample loader to automate database population, as well as a remote computation feature so users can offload computationally intensive tasks from the central GeNet server. In addition, the new release includes a DVD containing curated information on over 6,300 samples aggrega- ted from several public domain gene expression databases.

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.