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Amersham Biosciences, Roche

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Amersham Biosciences has launched its CodeLink Human P450 SNP Bioarray. The company expects drug makers to use the chip when screening clinical trial populations for individuals’ toxicogenomic profiles. Amersham also said the chip may be used to determine new phenotypes linked to P450 mutation. The chip genotypes 110 SNPs within nine P450 drug metabolism genes — CYP1A1, 1A2, 1B1, 2C9, 2C19, 2D6, 2E, 3A4, and 3A5. The release comes around three months after Roche launched its own cytochrome P450 product, called Amplichip. This product is the subject of a letter issued by the US Food and Drug Administration in July questioning why Roche had marketed the Amplichip as an analyte-specific reagent.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.