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Amersham Biosciences, Cell Engineering, SIRS-Lab, NuGEN Technologies, Isenseit, Affymetrix

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Amersham Biosciences introduced the CodeLink UniSet Human 20K I Bioarray, a 19,000 human gene product for its CodeLink microarrays, last week and introduced a kit for sample preparation.

 

Cell Engineering, a spinout of the Wales College of Medicine, last week announced the introduction of Slam, a line of micro-pipette products that use a lipid coating as a novel method for cell manipulation. The technology, developed in 1998 by the surgery department at the university, consists of coating pipettes with lipids, which, the company said, improve on micro-injection methods that damage cells through the stab of the micro-pipettes. The new products now being launched by CE consist of glass or quartz micro-pipettes that are capped with lipids that fuse with the lipid bilayer of the plasma membrane of the cell on contact. This permits material to be transferred from the micro-pipette to the cell interior or from the lipid cap of a micro-rod to the cell membrane without the cell being penetrated. As only a touch, not a “stab,” is required to gain access to the cell interior, there is no damage to the cell. The company has licensed the technology, which is patented by Wales College of Medicine, and is backed by the Wales Spinout program of the Welsh Development Agency, and equity held by the school, the researchers and venture investors.

 

SIRS-Lab of Jena, Germany, introduced four Lab-Arraytor human 60 biochips at BioAnalytika in Munich recently. The low- to mid-density chips have increased specificity, which has been achieved through optimization of length, specific GC-content and the melting point of the probes used. SIRS-Lab was spun out of Friedrich Schiller University and the Hans Knoll Institute of Jena.

 

NuGEN Technologies of San Carlos, Calif., introduced the Ovation Nanosample RNA Amplification System for gene expression profiling on commercial and self-spotted oligo and cDNA microarrays. The product can amplify from samples as small as 5 nanograms.

 

Isenseit of Germany will introduce iQconvert, a program that translates Affymetrix platform data into *.csy format, the company said. The product will become a component in the company’s iQmega suite.

The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.