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Amersham Biosciences


Amersham Biosciences last week announced the CodeLink UniSet Mouse 20K I Bioarray. The new array contains 20,289 30-mer probes for 21,108 mouse gene transcripts derived from public mRNA sequences in the UniGene and RefSeq databases and will be available for purchase in October, the company said. Pricing details were not provided. The arrays offer 108 positive controls, 300 negative controls, and 100 housekeeping genes. The new product offers a specificity of 90 percent probe-to-target sequence identity; sensitivity of less than one transcript per cell; and a dynamic response greater than three orders of magnitude, the company said. The mouse array is an upgrade over the company’s previous 10,000-gene mouse chips.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.