Aisin Seiki Kabushiki Kaisha, Jena-Optronik, Clinical Micro Sensors | GenomeWeb

Aisin Seiki Kabushiki Kaisha of Kariya, Japan, earned US Patent No. 6,541,227, “Preparation of labeled DNA.” The patent covers a system for the preparation of labeled DNA, using a complex triple-stranded DNA through an deoxyoligonucleotide complementary to the deoxyoligonucleotide sequence of the 3’ terminal sequence of a double-stranded DNA, followed by replacement of the 3’ terminal region of the plus strand of the double-stranded DNA with at least one labeled dNTP. The system also includes a method to immobilize the prepared DNA onto a solid support.


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