Aisin Seiki Kabushiki Kaisha of Kariya, Japan, earned US Patent No. 6,541,227, “Preparation of labeled DNA.” The patent covers a system for the preparation of labeled DNA, using a complex triple-stranded DNA through an deoxyoligonucleotide complementary to the deoxyoligonucleotide sequence of the 3’ terminal sequence of a double-stranded DNA, followed by replacement of the 3’ terminal region of the plus strand of the double-stranded DNA with at least one labeled dNTP. The system also includes a method to immobilize the prepared DNA onto a solid support.
Jena-Optronik of Jena, Germany, received US Patent No. 6,542,241, “Arrangement for optically reading out the information from substrates having a multiplicity of individual samples.” The patent covers a system for optically gathering information from radiation emitting from matrixed substrates containing individual samples. The system contains pixels reporting electronically to a receiver.
Clinical Micro Sensors of Pasadena, Calif., received US Patent No. 6,541,617, “Detection of target analytes using particles and electrodes.” The patent covers a biochip using binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence, or absence, of the target analyte to be determined.