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Aisin Seiki Kabushiki Kaisha, Jena-Optronik, Clinical Micro Sensors


Aisin Seiki Kabushiki Kaisha of Kariya, Japan, earned US Patent No. 6,541,227, “Preparation of labeled DNA.” The patent covers a system for the preparation of labeled DNA, using a complex triple-stranded DNA through an deoxyoligonucleotide complementary to the deoxyoligonucleotide sequence of the 3’ terminal sequence of a double-stranded DNA, followed by replacement of the 3’ terminal region of the plus strand of the double-stranded DNA with at least one labeled dNTP. The system also includes a method to immobilize the prepared DNA onto a solid support.


Jena-Optronik of Jena, Germany, received US Patent No. 6,542,241, “Arrangement for optically reading out the information from substrates having a multiplicity of individual samples.” The patent covers a system for optically gathering information from radiation emitting from matrixed substrates containing individual samples. The system contains pixels reporting electronically to a receiver.


Clinical Micro Sensors of Pasadena, Calif., received US Patent No. 6,541,617, “Detection of target analytes using particles and electrodes.” The patent covers a biochip using binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence, or absence, of the target analyte to be determined.

The Scan

WHO Seeks Booster Pause

According to CNN, the World Health Organization is calling for a moratorium on administering SARS-CoV-2 vaccine boosters until more of the world has received initial doses.

For Those Long Legs

With its genome sequence and subsequent RNAi analyses, researchers have examined the genes that give long legs to daddy longlegs, New Scientist says.

September Plans

The New York Times reports that the US Food and Drug Administration is aiming for early September for full approval of the Pfizer-BioNTech SARS-CoV-2 vaccine.

Nucleic Acids Research Papers on Targeting DNA Damage Response, TSMiner, VarSAn

In Nucleic Acids Research this week: genetic changes affecting DNA damage response inhibitor response, "time-series miner" approach, and more.