Agilent Technologies of Palo Alto, Calif., has received US Patent No. 6,790,620, “Small volume chambers.” Apparatus and methods are disclosed for forming a reaction chamber having relatively small volumes. An apparatus comprises two elements and a mechanism for introducing a gas to form a movable aerodynamic seal between the elements. One of the elements may have at least a portion of a device for dispensing reagents that are sealed and affixed therein.

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