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Agilent Technologies, Picoliter

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Agilent Technologies of Palo Alto, Calif., has received US Patent No. 6,939,673, "Manufacture of arrays with reduced error impact." The patent describes methods and apparatus for synthesizing a plurality of compounds such as biopolymers on a surface. An error in the deposition may occur in one or more of the plurality of steps and a reagent for forming the chemical compounds is deposited on the surface of the support. A determination is made as to whether an error occurred in the depositing of the reagent. If an error is detected, the support is treated to re-deposit at least some of those reagents that were not correctly deposited.


Picoliter of Sunnyvale, Calif., has received US Patent No. 6,938,987, "Acoustic ejection of fluids from a plurality of reservoirs." The patent describes a method and device for the acoustic ejection of fluid droplets from each of a plurality of fluid-containing reservoirs. The droplets are ejected toward sites on a substrate surface for deposition. The device is comprised of a plurality of reservoirs each adapted to contain a fluid; an ejector comprising a means for generating acoustic radiation and a means for focusing the generated acoustic radiation so that fluid droplets from the reservoir fluids is ejected; and a means for positioning the reservoirs in acoustically coupled relationship to the ejector. The invention is useful in a number of contexts, particularly in the preparation of biomolecular arrays.

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