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Agilent Technologies, Picoliter


Agilent Technologies of Palo Alto, Calif., has received US Patent No. 6,939,673, "Manufacture of arrays with reduced error impact." The patent describes methods and apparatus for synthesizing a plurality of compounds such as biopolymers on a surface. An error in the deposition may occur in one or more of the plurality of steps and a reagent for forming the chemical compounds is deposited on the surface of the support. A determination is made as to whether an error occurred in the depositing of the reagent. If an error is detected, the support is treated to re-deposit at least some of those reagents that were not correctly deposited.

Picoliter of Sunnyvale, Calif., has received US Patent No. 6,938,987, "Acoustic ejection of fluids from a plurality of reservoirs." The patent describes a method and device for the acoustic ejection of fluid droplets from each of a plurality of fluid-containing reservoirs. The droplets are ejected toward sites on a substrate surface for deposition. The device is comprised of a plurality of reservoirs each adapted to contain a fluid; an ejector comprising a means for generating acoustic radiation and a means for focusing the generated acoustic radiation so that fluid droplets from the reservoir fluids is ejected; and a means for positioning the reservoirs in acoustically coupled relationship to the ejector. The invention is useful in a number of contexts, particularly in the preparation of biomolecular arrays.

The Scan

Dropped Charges

The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal.

More Kids

The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children.

PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS

In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more.

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.